Hair loss affects millions worldwide, with up to 50% of women and 80% of men experiencing some degree of hair thinning in their lifetime. Despite the availability of numerous treatments, many individuals struggle to find solutions that work for them. The challenge lies in the fact that hair loss is not a one-size-fits-all problem; it requires a personalized approach tailored to individual needs and hair types.
A groundbreaking clinical study published in the Journal of Drugs in Dermatology (JDD) has introduced a revolutionary AI-based approach to hair loss treatment developed by MDalgorithms Inc., the company behind MDhair and MDacne. This 24-week clinical trial tested the effectiveness of customized, non-medicated hair treatment regimens designed based on artificial intelligence (AI) assessments. This study was an IRB-approved, independent clinical study conducted by a top clinical research center in the United States, ensuring rigorous methodology and unbiased results. The results? Significant reductions in hair shedding, improved scalp health, and increased hair density. Let's dive into the key findings and benefits of this cutting-edge approach.
The Need for Personalized Hair Loss Treatment
Traditional hair loss treatments often fail because they do not account for individual variations in scalp health, hair type, and underlying causes of hair thinning. Many consumers spend time and money on products that may not suit their conditions. This is where AI-powered customization makes a difference.
The MDhair system uses a proprietary AI model that analyzes scalp images and questionnaire responses to create a personalized regimen. The AI was trained on 47,000 images of people with hair loss and utilizes deep learning to assess hair thinning severity, identifying the most effective treatment for each user.
The Clinical Study: Key Findings
The clinical trial involved 38 women aged 34 to 65 who reported self-perceived hair thinning. They were provided with customized treatment kits, which included combinations of topical serums, shampoos, oral supplements, and marine collagen peptides.
To ensure the benefits of the treatment were measured objectively, several laboratory techniques were employed. These techniques allowed researchers to validate the treatment's effectiveness in a scientifically rigorous manner.
The hair-shedding wash test quantified the number of hairs lost during washing, providing a reliable metric of hair retention improvement. Transepidermal water loss (TEWL) measurements assessed scalp hydration and barrier function, with lower values indicating better scalp health. Additionally, scanning electron microscopy (SEM), conducted in a university lab, provided high-resolution images of hair strand surfaces, revealing structural improvements such as smoother cuticles and reduced damage. These techniques allowed researchers to validate the treatment's effectiveness in a scientifically rigorous manner.
Key Findings
- 88.9% of participants reported overall hair improvement
- 85.2% experienced better scalp health
- 92.6% noticed less hair brittleness
- 69% decrease in transepidermal water loss (TEWL), indicating improved scalp barrier function and hydration
- 37.3% reduction in hair shedding at 12 weeks and 32.4% reduction at 24 weeks
- No adverse events were reported.
The results of this study highlight the effectiveness of a personalized, data-driven approach compared to generic treatments that often yield inconsistent results.
How MDhair Works
Step 1: AI-Driven Hair Analysis
Participants submitted scalp images via MDhair's mobile web app, which the AI system processed. The AI-generated heatmaps highlighted areas of hair thinning, allowing for precise assessment.
Step 2: Customized Treatment Plan
Based on the AI analysis, each participant received a unique combination of products, including:
- Topical serums and shampoos with key ingredients such as saw palmetto, green tea extract, and caffeine to block DHT and stimulate hair growth.
- Oral supplements enriched with biotin, vitamins, and minerals to support scalp and hair health from within.
- Marine collagen peptides enhance hair strength and elasticity.
Step 3: Continuous Tracking and Adjustments
Users followed their customized regimen and were monitored at different intervals (weeks 4, 8, 12, and 24). Hair shedding was measured using a standardized wash test, and scalp hydration was assessed using TEWL measurements.
The Benefits of a Comprehensive Approach
A key advantage of MDhair’s approach is its ability to target the root cause of hair loss from multiple angles. By addressing hair health both externally and internally, this comprehensive strategy ensures maximum effectiveness. Custom-tailored scalp treatment serums and shampoos work directly on the scalp to promote circulation, reduce inflammation, and balance oil production, creating an optimal environment for hair growth. Meanwhile, oral supplements and marine collagen peptides nourish hair from within, providing essential vitamins, minerals, and amino acids that strengthen hair follicles and improve overall scalp health. This dual-action method enhances hair density, reduces shedding, and fosters stronger, more resilient hair over time.
Why This Approach Stands Out
1. Data-Backed Results
Unlike traditional over-the-counter hair products, the AI-based treatment model ensures that the regimen is tailored to individual needs, leading to superior outcomes.
2. Comprehensive Care
MDhair’s approach combines topical and oral solutions, addressing hair loss from multiple angles. This holistic strategy has proven to be more effective than single-product solutions like minoxidil.
3. Scalp Barrier Improvement
TEWL measurements demonstrated significant improvements in scalp hydration and barrier function, a crucial factor in maintaining a healthy environment for hair growth.
4. Positive Patient Experience
Participants not only experienced physical improvements but also reported increased confidence and satisfaction with their hair health.
A Game Changer in Hair Loss Treatment
The MDhair study marks a major shift in how hair loss is treated. By leveraging AI and clinical data, MDhair offers a personalized, effective, and accessible solution for women struggling with hair thinning. This innovative approach empowers individuals with data-driven recommendations, ensuring they receive the best possible care for their unique needs.
As hair loss continues to be a prevalent concern, AI-driven customization represents the future of dermatology and trichology. With MDhair, individuals no longer have to rely on trial-and-error methods—now, they can trust science and technology to guide them toward healthier, fuller hair.
Reference
Bhardwaj V, Rodgers N, Harth O, Harth Y. Artificial Intelligence-Based Personalization of Treatment Regimen for Hair Loss: A 6-Month Clinical Trial. J Drugs Dermatol. 2025;24(3):233-238.
Find the most effective hair growth products for you by taking the free hair assessment.
