Your Cart is Empty

Start your journey to clear skin.

Take the quiz Shop all products
ARTICLES / DIET

Hair loss while fasting? This one ingredient can help!

Yoram Harth, MD
By Yoram Harth, MD | Feb 26, 2025

Intermittent fasting (IF) has gained popularity for its weight loss, metabolism, and overall health benefits. Many use it to improve digestion, boost energy, and even support longevity. However, a surprising side effect has emerged—hair loss. You're not alone if you’ve been practicing intermittent fasting and noticing increased shedding or slower hair growth. Recent research highlights how fasting can disrupt hair health, but the good news is that there may be a simple solution: topical vitamin E.

Why Does Intermittent Fasting Cause Hair Loss?

Hair growth depends on a cycle that involves hair follicle stem cells (HFSCs). These cells activate during growth phases to produce new hair. When HFSCs are healthy and functioning properly, hair remains strong and thick. However, new research suggests that intermittent fasting can disrupt this process in several ways:

  1. Hormonal Changes: Fasting increases levels of cortisol and epinephrine. These stress-related hormones trigger changes in the body’s metabolism, including the breakdown of fat stores.
  2. Fat Breakdown (Lipolysis): When fasting, the body shifts to burning stored fat for energy. This process, known as lipolysis, releases free fatty acids (FFAs) into the bloodstream and near hair follicles.
  3. Oxidative Stress: An excess of free fatty acids can create oxidative stress, which can damage cells. Hair follicle stem cells (HFSCs) are particularly sensitive to oxidative stress.
  4. HFSC Apoptosis (Cell Death): As oxidative stress increases, HFSCs begin to die off. Without these stem cells, hair follicles struggle to regenerate, causing hair thinning and increased shedding.
  5. Slower Hair Cycle: IF-induced stress prolongs the hair cycle's resting phase (telogen), delaying the start of new growth.

While intermittent fasting provides numerous health benefits, these disruptions can result in noticeable hair thinning, slower regrowth, and even long-term hair loss if left unaddressed.

How Can Vitamin E Help Prevent Fasting-Related Hair Loss?

Scientists studying this problem discovered that topical vitamin E can counteract the negative effects of fasting on hair follicles. Here’s how it works:

  1. Fights Oxidative Stress: Vitamin E is a powerful antioxidant that neutralizes free radicals and reduces oxidative stress, protecting HFSCs from damage.
  2. Supports Scalp Health: Vitamin E improves circulation and nourishment to the scalp, creating a better environment for hair follicles to thrive.
  3. Prevents HFSC Death: Vitamin E helps preserve HFSCs by lowering oxidative stress, ensuring they continue to regenerate new hair.
  4. Encourages Faster Growth: With reduced stress and healthier follicles, hair moves out of the resting phase more quickly, leading to faster regrowth.

In a study published in Cell Research (2025), researchers applied topical vitamin E to fasting mice and observed a significant reduction in hair follicle stem cell damage. Unlike the untreated fasting group, the treated mice maintained normal hair growth, which experienced significant hair loss.

How to Use Vitamin E for Hair Protection During Fasting

If you’re practicing intermittent fasting and concerned about hair loss, adding vitamin E to your hair care routine may help prevent shedding and support regrowth. Here’s how you can use it effectively:

Choose a High-Quality Topical Vitamin E Oil or Serum

  1. Look for natural vitamin E (tocopherol) products rather than synthetic ones.
  2. Some serums combine vitamin E with other hair-boosting ingredients like biotin and rosemary oil for extra benefits.

Apply Directly to the Scalp

  1. Massage a few drops of vitamin E oil or serum into the scalp.
  2. Focus on thinning areas or regions where shedding is noticeable.
  3. For best results, apply before bedtime and leave it overnight.

Combine with a Nourishing Shampoo and Conditioner

  1. Look for hair products that include vitamin E as an ingredient.
  2. Avoid harsh sulfates or alcohol-based products that can dry out the scalp.

Use 2-3 Times a Week

  1. Consistent use is key. Applying vitamin E regularly will help maintain scalp health and prevent further damage.

Pair with a Nutrient-Rich Diet

  1. While topical application is highly effective, eating vitamin E-rich foods (like nuts, seeds, avocados, and spinach) can further support overall hair health.

Best Products to Prevent Intermittent Fasting-Related Hair Loss

For those looking for an effective solution, MDhair serums and supplements offer a targeted approach to combat fasting-related hair loss. The MDhair Topical Scalp Serum is infused with vitamin E, biotin, and other antioxidants to protect hair follicle stem cells from oxidative stress and enhance scalp health. This serum helps prevent hair thinning by nourishing follicles and promoting stronger, healthier hair. MDhair’s Oral Hair Growth Supplements also contain a blend of vitamin E, saw palmetto, and collagen peptides, which work internally to support hair regrowth and prevent excessive shedding. By combining topical and oral treatments, MDhair provides a comprehensive solution for those experiencing hair loss due to intermittent fasting.

The Role of Other Key Nutrients in Hair Health

While vitamin E plays a significant role in protecting hair during intermittent fasting, other essential vitamins and minerals are also crucial. MDhair’s Restore and Regrowth Supplements include ingredients such as biotin, zinc, iron, and vitamin D, which support overall hair follicle function and scalp health. Biotin helps strengthen hair strands, zinc regulates hair follicle activity, and iron prevents hair thinning by supporting oxygen transport to hair roots. Marine collagen hydrolyzed peptides also provide essential amino acids that improve hair strength, elasticity, and resilience. Since fasting can reduce protein intake, supplementing with marine collagen helps compensate for this deficiency, promoting stronger and healthier hair growth in those practicing intermittent fasting.

Additional Tips to Minimize Hair Loss While Fasting

In addition to using topical vitamin E, here are a few more ways to keep your hair strong during intermittent fasting:

  • Stay Hydrated: Dehydration can worsen hair thinning. Drink plenty of water throughout the day.
  • Eat Nutrient-Dense Meals: Make sure your eating window includes protein, iron, omega-3s, and vitamins like B12 and D, which are essential for hair growth.
  • Reduce Stress: Practicing mindfulness, meditation, or yoga can help lower cortisol levels and reduce stress-related hair shedding.
  • Avoid Excessive Fasting: Consider modifying your fasting schedule if you notice significant hair loss. Shortening fasts or incorporating more nutrient-dense meals may help.

Final Thoughts

While intermittent fasting has many health benefits, it can also lead to unexpected side effects like hair loss due to hormonal shifts and oxidative stress. Fortunately, topical vitamin E has shown great potential in protecting hair follicle stem cells, reducing oxidative stress, and promoting hair regrowth. If you’re experiencing fasting-related hair thinning, incorporating vitamin E into your routine may be the best solution to maintain healthy, strong hair while continuing your fasting journey.

By making simple adjustments—using vitamin E, maintaining a nutrient-rich diet, and staying hydrated—you can enjoy the benefits of intermittent fasting without worrying about losing your hair.

More info:

Does intermittent fasting cause hair loss?

Shop

MDhair Regrowth Serum
MDhair Restore Serum
MDhair Marine Collagen
MDhair's Restore supplements

References

  1. Galvan C, Lowry WE. Hangry hairs: intermittent fasting linked to hair loss. Cell Res. 2025;0:1-2. doi:10.1038/s41422-025-01082-y.
  2. Haraguchi K, Sugawara K, Soga S, et al. Intermittent fasting and its impact on hair follicle stem cell dynamics. Cell Res. 2025;35(2):112-126.
  3. Patel AB, Smith RD, Khosla C. The role of oxidative stress in hair loss: Mechanisms and interventions. J Dermatol Sci. 2024;104(3):145-158.
  4. Kim J, Park T, Lee HY. Hormonal changes during intermittent fasting and their effects on hair follicle cycling. Endocr Metab Immune Disord Drug Targets. 2024;24(1):38-50.
  5. Wang X, Chen Y, Liu Z. Free fatty acids and oxidative stress in fasting-induced hair loss. J Invest Dermatol. 2023;143(5):873-884.
  6. Zhao L, Zhang H, Wang J. Cortisol-induced telogen phase prolongation in fasting conditions. Exp Dermatol. 2023;32(11):1498-1507.
  7. Ahmed S, Lakhani NN, Riaz M. The impact of dietary patterns on hair follicle health: A systematic review. Nutrients. 2024;16(2):411.
  8. Singh R, Chatterjee A, Das A. Vitamin E as an antioxidant therapy for hair loss. Clin Cosmet Investig Dermatol. 2024;17:57-69.
  9. Maeda T, Kuroda K, Takahashi R. Topical vitamin E application and its protective effects on hair follicle stem cells. J Cosmet Dermatol. 2025;24(1):22-34.
  10. Jones L, Peters M, Greene K. Biotin and vitamin E supplementation for hair growth: A clinical trial. J Clin Aesthet Dermatol. 2023;16(8):25-32.
  11. Hirose Y, Tanaka T, Sato K. Lipolysis and its influence on scalp health during fasting. Arch Dermatol Res. 2023;315(9):1321-1335.
  12. Malik M, Javed F, Hussain S. Nutritional deficiencies and hair loss: The role of iron, zinc, and vitamins. Int J Trichology. 2024;16(1):3-12.
  13. Becker C, Wilson K, Young A. Role of marine collagen peptides in hair growth and resilience. J Dermatol Treat. 2024;35(5):789-798.
  14. Shen Y, Guo X, Lu Y. Intermittent fasting-induced changes in scalp microbiome and hair health. Front Cell Infect Microbiol. 2024;14:1134567.
  15. Chen J, Yang H, Sun Q. The effects of stress hormones on hair follicle apoptosis. Mol Cell Endocrinol. 2023;569:112114.
  16. Patel P, Kumar N, Shah M. Topical antioxidants in dermatology: Mechanisms and clinical applications. J Drugs Dermatol. 2024;23(2):189-198.
  17. Liao W, Zhou X, Liu J. Nutritional strategies to mitigate hair loss in fasting individuals. Adv Nutr. 2024;15(3):678-690.
  18. Zhang R, Wang L, Li F. Hair follicle regeneration and stem cell survival under metabolic stress. Stem Cells Transl Med. 2024;13(7):1023-1034.
  19. Williams R, Carter T, Evans D. The impact of hydration on hair health: A review. J Clin Dermatol Res. 2023;11(4):276-285.
  20. Yoon S, Kim H, Lee C. The synergistic effects of vitamin E, biotin, and rosemary oil on hair growth. Phytother Res. 2024;38(1):145-157.
  21. Sato M, Inoue K, Nakamura Y. Modulating fasting duration to prevent hair loss: A clinical study. Nutr Metab (Lond). 2025;22(1):87.

Find the most effective hair growth products for you by taking the free hair assessment.

Start Your journey to thicker, healthier hair.

  • Get your customized treatment plan in minutes.
  • Unlock unlimited dermatologist chat support.
  • Receive ongoing expert supervision for real-time adjustments.

TAKE THE QUIZ